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Tracy Centanni

Tracy (Rosen) Centanni

Tracy M Centanni, PhD

Post Doctoral Researcher
McGovern Institute for Brain Research
Massachusetts Institute for Technology
Cambridge, MA 02139  

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46-4037C

I graduated with my PhD in Neuroscience in 2013 from the University of Texas at Dallas. I use neural imaging, behavioral, and genetic testing methods in rodent models and in humans to investigate the neural and genetic basis of language and communication impairments.

Here in the Gabrieli lab, I am currently using MEG and fMRI in humans to test several hypotheses from my work in the rat model. Specifically, I am looking into the neural and genetic mechanisms of dyslexia and language perception. My long term research goals are to develop an independent research program to investigate the variety of genes involved in impairments such as dyslexia, specific language impairment, and autism by using a combination of animal models and human participants. Please visit my website for additional information about my work.


Publications:

TM Centanni, AB Booker, F Chen, AM Sloan, RS Carraway, RL Rennaker, JJ LoTurco, MP Kilgard (2016). Knockdown of dyslexia-gene Dcdc2 interferes with rapid speech sound discrimination, The Journal of Neuroscience. 36(17): 4895-4906, doi: 10.1523/JNEUROSCI.4202-15.2016

CT Engineer, KC Rahebi, MS Borland, EP Buell, TM Centanni, MK Fink, KW Im, LG Wilson, MP Kilgard (2015). Degraded neural and behavioral processing of speech sounds in a rat model of Rett Syndrome. Neurobiology of Disease. 83: 26-34.

TM Centanni, JR Green, J Iuzzini-Seigel, CW Bartlett, TP Hogan (2015). Evidence for gains at 15q11.2 as a susceptibility factor for inherited language impairment. Frontiers in Genetics. 6:272, doi: 10.3389/fgene.2015.00272.

TM Centanni, JN Sanmann, JR Green, J Iuzzini-Seigel, C. Bartlett, WG Sanger, TP Hogan (2015). The role of candidate-gene CNTNAP2 in childhood apraxia of speech and specific language impairment. American Journal of Medical Genetics, part b; doi: 10.1002/ajmg.b.32325.

K Farquharson, TM Centanni, C Franzluebbers, TP Hogan (2014). Phonological and lexical influences on phonological awareness performance in children with Specific Language Impairment and Dyslexia. Frontiers in Educational Psychology; 5:838, doi: 10.3389/fpsyg.2014.00838.

AC Reed, TM Centanni, MS Borland, CJ Matney, CT Engineer, MP Kilgard (2014). Behavioral and neural discrimination of speech sounds after moderate or intense noise exposure in rats. Ear and Hearing; doi: 10.1097/AUD.0000000000000062.

CT Engineer TM Centanni, KW Im, KC Rahebi, WA Vrana, NA Moreno, MP Kilgard (2014). Speech training improves auditory cortex responses to speech sounds in a rat model of autism. Frontiers in Systems Neuroscience; 8:137, doi: 10.3389/fnsys.2014.00137.

TM Centanni, AB Booker, AM Sloan, F Chen, BJ Maher, RS Carraway, N Khodaparast, JJ LoTurco, MP Kilgard (2014). Knockdown of the dyslexia-associated gene KIAA0319 impairs temporal responses to speech stimuli in rat primary auditory cortex. Cerebral Cortex; 24(7): 1753-66.

TM Centanni, F Chen, CT Engineer, AB Booker, RL Rennaker, JJ LoTurco, MP Kilgard (2014). Speech sound processing deficits and training-induced neural plasticity in rats with dyslexia gene knockdown. PLOS one; 9(5): e98439. doi: 10.1371/journal.pone.0098439.

CT Engineer, TM Centanni, KW Im, KC Rahebi, EP Buell, MP Kilgard (2014). Degraded speech sound processing in a rat model of Fragile X syndrome. Brain Research; 1564: 72-84.

CT Engineer, TM Centanni, KW Im, MS Borland, NA Moreno, RS Carraway, LG Wilson, MP Kilgard (2014). Degraded auditory processing in a rat model of autism limits the speech representation in non-primary auditory cortex. Developmental Neurobiology; doi: 10.1002/dneu.22175.

TM Centanni, AM Sloan, AC Reed, CT Engineer, RL Rennaker, MP Kilgard (2014). Detection and identification of speech sounds using cortical activity patterns. Neuroscience; 258: 292-306.

TM Centanni, CT Engineer, MP Kilgard (2013). Cortical speech-evoked response patterns in multiple auditory fields are correlated with behavioral discrimination ability. Journal of Neurophysiology; 110(1): 177-189.

Additional information